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The effect of copper on the GM has also been demonstrated in Nile tilapia, where exposure to subacute levels (0,5 mg/L, 1 mg/L and 2 mg/L Cu 2+ ) for 14 days resulted in reduced bacterial diversity, a decreased abundance of Ruminococcus and Shigella and increased abundance of Edwardsiella and Aquabacterium (Zhang et al., 2022a)

Inflammopharmacol 20:12750 Nguyen T, Sherratt PJ, Pickett CB (2003) Regulatory mechanisms controlling gene expression mediated by the antioxidant response element

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Orthopedic Reviews 17(1):12313605