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The HPLC chromatogram should show one dominant peak at the expected retention time with minimal secondary peaks

Monitoring during this phase ensures that the body continues to respond well to the medication

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Lung histology

The kynurenine pathway (KP) is the major metabolic pathway in which tryptophan (TRP) is the key precursor which is further converted into a variety of neuroactive substances that can have both neurotoxic metabolites (Quinolinic acid) and neuroprotective metabolites such as kynurenic acid, and picolinic acid