Toxine bleiben am Glutathion-Molekl haften, werden durch den Krper transportiert und anschlieend ausgeschieden
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-Syn oligomers cause massive degeneration and loss of nigrostriatal dopaminergic neurons, in turn inducing PD through multiple mechanisms, involving mitochondrial dysfunction, endoplasmic reticulum stress, proteasomal influences, neuroglial cellular and inflammatory responses, membrane damage, synaptic dysfunction, autophagy and lysosomal dysfunction (Bengoa-Vergniory et al., 2017)
doi: 10.3389/fimmu.2020.610363 6 YooSKMehdiSFPusapatiSMathurNAnipindiMLunenfeldBet al