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These changes can cause oxidative modifications to reactive thiols of structurally- or functionally-critical proteins, such as transcription factors 43 , signal transduction molecules 44 or metabolic enzymes 45 , and thereby evoke cellular defense mechanisms against oxidative damage 46

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Naturally produced in the liver, it plays a central role in neutralizing free radicals, detoxifying harmful compounds, and supporting immune function

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Isorhamnetin promotes functional recovery in rats with spinal cord injury by abating oxidative stress and modulating M2 macrophages/microglia polarization

Published human studies evaluating AOD 9604 primarily used oral doses ranging from 1-5 mg daily