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This genetic context may help provide insight into treatment response variability and support more informed medication selectionwhether compounded semaglutide, tirzepatide, or combination formulations

Overall, incretin hormones contribute to energy balance by suppressing glucagon secretion, delaying gastric emptying, and promoting satiety through direct actions on the central nervous system [24, 25]

These data demonstrated the novel GLP-1R/cAMP/Epac/PI3K/Akt signaling pathway for cardioprotective effects in H9c2 cells