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doi: 10.1677/JOE-06-0148 112 GilbertMPPratleyRE

Both medications reduce appetite through different pathways, and their combined effect might lead to inadequate caloric and nutrient intake, potentially causing muscle loss, vitamin deficiencies, or metabolic complications

If you struggle to eat enough protein or calories, liquid nutrition like bone broth or protein shakes can bridge gaps without requiring large chewing effort

This discrepancy suggests that factors beyond connexins may contribute to hepsin's protective role

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