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In addition, both riboflavin and PLP are essential determinants of the kynurenine pathway which influence glutamate receptors, hence, glutamate excitotoxicity potential, as shown in Section Riboflavin as a Determinant of the Kynurenine Pathway. Concerning PD, glutamate excitotoxicity contributes to dopaminergic neuronal loss (84)

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Paeoniflorin exerts neuroprotective effects in a transgenic mouse model of Alzheimers disease via activation of adenosine A(1) receptor

Intravenous N -acetylcystine: the treatment of choice for paracetamol poisoning