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Some dormant follicles that were in telogen phase begin transitioning back to anagen

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This implies sodium channel inhibition, a blockade of voltage-gated sodium channels (VGSCs) leading to a reversible block of action potential propagation [278], and reduced permeability of cell membranes, thereby blocking depolarization and preventing the conduction of the electrical impulse through which pain occurs [279]

Dermatologically evaluated with a skin irritation score of 0.00 and classified as non-irritating (Excellent) after a 24-hour patch application.

Then, using a LightCycler480 (Roche Diagnostics, United States), quantitative real-time PCR was carried out using Hieff UNICON Universal Blue qPCR SYBR Green Master Mix (11184ES08, Yeasen Biotechnology Co., Ltd., Shanghai, China)

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