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23 Rapid weight loss after gastric bypass, biliopancreatic diversion or sleeve gastrectomy has been reported to initiate gallstone formation in 30% of patients during the first six to 12 months after surgery

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Tirzepatide is a dual agonist of GIP and GLP-1 receptors, acting in an integrated way across incretin pathways.It increases insulin secretion in a glucose-dependent manner and improves glycaemic regulation (reducing peaks and variability)

WADA is expected to evaluate whether to formally prohibit incretin receptor agonists in future cycles

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