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Metformin limits ceramide-induced senescence in C2C12 myoblasts

The result is a smoother, more youthful look with visibly diminished under-eye bags

doi: 10.1186/s13024-020-00397-1 269 SwindellW

To achieve this objective, critical research priorities in subsequent clinical trials include: standardization of ESCM extracts, determination of safe dosage ranges, the differences in bioavailability of each constituent and their corresponding combination methods, as well as the development of personalized therapeutic regimens stratified by cancer subtypes

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