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Combine this with the dehydration commonly caused by these medications , and you can experience significant full-body aches, leg cramps, and injection-site soreness

[13] These are typical GLP-1 side effects and are usually mild to moderate in severity

Glucagon receptor agonism increases resting energy expenditure, promotes hepatic fat oxidation, and drives thermogenesis

Cost-effectiveness of once daily GLP-1 receptor agonist lixisenatide compared to bolus insulin both in combination with basal insulin for the treatment of patients with type 2 diabetes in Norway

17 Moreover, other trials as the SUSTAIN-6 trial showed that semaglutide, another GLP-1RA also reduced the risk of MACE by 26% and non-fatal stroke by 39% in patients with T2DM