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Harman, L.S., C

The benefits of GLP-1 RAs in patients with obesity and type 2 diabetes are large, and clinically significant, including weight loss, reduction in major cardiovascular events, improved kidney outcomes, decreased cardiovascular and all-cause mortality, improvement of glucose control and reduction of hepatic steatosis

Blood and tissue processing For all studies blood was drawn by cardiac puncture in anesthetized mice and collected in 5 l EDTA (BD medical) before being spun in a microcentrifuge at 9.8 revolutions per minute (RPM) for 5 min at room temperature

Frontiers in Nutrition, 6 , 146

Individuals with type 2 diabetes often have impaired insulin function or insulin resistance

Lyophilization, or freeze-drying, is a sophisticated process used to preserve delicate biological materials