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Among them, HLA alleles, especially the HLA-DR1 and HLA-DR4 loci, play an important role in the development of RA by mechanisms that may be related to the formation of citrullinated antigens and immune tolerance of CD4 + T cells (Wysocki et al., 2020

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N-acetyl cysteine, for example, can fuel histamine responses

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This gene encodes a glutathione S-transferase belonging to the alpha class

These therapies target neurotransmitter systems, neuroplasticity, and mitochondrial function within the brain