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L-citrulline significantly increases plasma arginine levels, restores the substrate availability of endothelial nitric oxide synthase (eNOS), and promotes enzyme coupling

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Trials also commonly tracked fasting glucose and HbA1c at 8-12 weeks because GH opposes insulin, and a subset of trial subjects developed measurable glucose elevation over time

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Butyrate-producing bacterial groupssuch as Ruminococcaceae , the Eubacterium rectale group, Lachnospiraceae , and Erysipelotrichaceae are reduced in children with ASD, while the abundance of Clostridium is significantly increased (Liu et al., 2019