Given that GLP-1-RAs alter gut motility and secretion, and that the gut microbiota can influence host eating behavior, including food preferences, it is plausible that these drugs indirectly influence taste perception by modulating microbial composition and the subsequent production of metabolites that can signal to the brain, potentially via vagal afferents or systemic circulation
Understanding these variables helps explain why responses to treatment may differ between patients
Sharma T, Das N, Ismail B, et al
Xie Z et al
Many patients blame themselves, even though obesity is a disease of disordered appetite and biological origin, not simply the result of habits or willpower, he said
Crossen S, Raymond J, Neinstein A (2020) Top 10 tips for successfully implementing a diabetes telehealth program