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Clinical trials demonstrate remarkable efficacy in treating withdrawal symptoms, with 97% of opiate-dependent and 87% of alcohol-dependent patients experiencing symptom relief

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The aforementioned considerations imply that Nrf2 may be considered a target in some situations, thus supporting a possible use of specific inhibitors, or rather a defensive weapon to activate, thus stimulating the interest towards its activators

doi:10.1309/cvhkle2r4w68k2nq

Peer review Peer review information Nature Catalysis thanks Steffen N Lindner, Diethard Mattanovich and the other, anonymous, reviewer(s) for their contribution to the peer review of this work