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For people whove gained weight on mirtazapine, Wegovy may help counteract this effect

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Supplements, NSAIDs, and Pancreatitis Risk Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and naproxen are safe to use occasionally with semaglutide, but chronic NSAID use increases the risk of gastrointestinal bleeding, especially when combined with GLP-1's effects on stomach function

Data on one do not automatically transfer to the other