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Dig Dis Sci 1988;33:409-13

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In a healthy pregnancy, the maternal immune system is constantly altered to accommodate the needs of the growing fetus, and melatonin acts as a key anti-inflammatory by regulating immune homeostasis during early and late gestation

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100 A recent Phase 2b trial in obese individuals demonstrated that 32 weeks of treatment with danuglipron at doses ranging from 40 to 200 mg twice daily resulted in an average weight loss of 11.7%, whereas the placebo group exhibited 1.4% weight gain

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