doi: 10.3389/fgene.2021.612501 Received 30 September 2020 Accepted 15 March 2021 Published 20 April 2021 Volume 12 - 2021 Edited by Yuriy L
3,4 American Association of Clinical Endocrinology guidelines recommend treatment with GLP-1RA in T2DM patients with coexisting ASCVD, high-risk for ASCVD, heart failure, or chronic kidney disease regardless of their glycemic control due to their organ protective effects
Without enough GLP-1 the brain cant be healthy
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GLP-1 receptors are expressed in several key regions implicated in addiction and reward processing, including the ventral tegmental area (VTA), nucleus accumbens, amygdala, hippocampus, and lateral hypothalamus
It works by replicating the bodys natural hormone GLP-1, which is responsible for regulating appetite, digestion, and blood sugar balance