About 1020% of patients are non-responders or modest responders
Since vitamin B12 is water-soluble, excess amounts are excreted through urine, reducing the risk of toxicity
Though there are other, more compelling novels, on this subject, this one is a quick read
If you are prone to motion sickness or have a sensitive stomach first thing in the morning, evening dosing might prove gentler
Some studies have also observed the effect of acupuncture on traditional Chinese medicine syndromes of VD patients, and it was found that acupuncture at Baihui (GV20), Sishencong (EX-HN1), Shenting (GV24), Danzhong (CV17), Zhongwan (CV12), Qihai (CV6), Xuehai (SP10), Zusanli (ST36) and Neiguan (PC6) is more effective in treating excess syndromes, such as Liver-yang hyperactivity or phlegm obstruction of the orifices than deficiency syndromes such as kidney essence deficiency (Shi et al., 2014)
The 2012 New England Compounding Center outbreak documented what happens when even professional compounding environments fall short of sterility standards contaminated injectable methylprednisolone resulted in 751 fungal infections and 64 deaths across 20 states