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The vascular improvements may enhance BDNF delivery to brain regions by improving blood flow to the hippocampus and cortex

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Although rupture of the plasma membrane represents the terminal event of ferroptotic death, emerging evidence indicates that ferroptotic signaling is initiated at intracellular membrane compartments, including the ER, Golgi-associated vesicles, and lysosomes 107-110

The investigators remarked that This suggests that patients with [end-stage renal disease] may benefit from the anti-inflammatory effects of NAC (Saddadi 2014)

This concern comes up regularly, and it is worth addressing directly

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