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Effective alternatives during the adjustment period: Leg press instead of heavy free-weight squats Machine press instead of barbell bench press (easier to bail safely) Seated rows instead of bent-over rows (less abdominal compression) In general, machine-based exercises work well in times of low energy
The covariate models were parameterised as follows for the i th individual: and the effect of drug product strength on the rate of absorption was described as Covariate relationships were described as follows: In the above equations, represents an estimated value for a covariate and represents between-subject variability
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