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A 2024 systematic review cataloged the preclinical BPC-157 literature and identified a consistent pattern: strong effect sizes in rodent models across multiple injury types, with no dose-limiting toxicity observed at standard experimental doses [10]

The results indicated that after drug intervention, the number of differentially expressed genes between the caffeine and HFHC groups was more than three times that which was observed between the EGCG and HFHC groups

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