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In women with PCOS, high concentrations of leptin have been reported to inhibit the expression of aromatase mRNA in granulosa cells, while the hyperandrogenic follicular environment in GCs was found to significantly reduce the expression of P450arom, which can convert androgens into estrogen, further increasing the levels of androgens and ultimately promoting follicular atresia (148150)

(2021) 31:e2221

Key outcomes included: Reversal of memory loss Restoration of LTP Increased dendritic spine density This has led to Dihexa being nicknamed the synapse builder in the peptide community

Stable in lyophilised form

Sosa, V

Carbohydrate co-ingestion