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Contact your prescriber if side effects are severe or significantly impact your quality of life

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Patients with a history of this condition should have regular eye exams while using these medications

The study results, published in the July 15, 2026, online edition of The Lancet Gastroenterology & Hepatology , address a major unmet need for people with metabolic dysfunctionassociated steatohepatitis (MASH), a serious form of fatty liver disease that can lead to cirrhosis, liver failure, and the need for transplantation

Clinical trials show retatrutide results in significant weight loss (up to 24.2%) and improved glycemic control, making it a beneficial treatment for obesity and diabetes