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Question 3: Do you want the FDA-approved branded product specifically

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the 2.4 mg dose produced 16.9%, only 3.7% more despite more than doubling the dose and significantly increasing GI side effects (Wilding et al., NEJM 2021)

In both types of testing, however, there will be some form of relation between dose (exposure) and effect, as the capacity of a substance to produce effects, its potency, will be represented by the dose (exposure) required to produce sensitization (or toxicity)

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