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The basis of the development of AITD - Hashimotos thyroiditis (HT), Graves disease (GD), Graves ophthalmopathy (GO) is the loss of immune tolerance to thyroid antigens - thyroid peroxidase (TPO), thyroglobulin (Tg) and thyroid-stimulating hormone receptor (TSH-R)

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This acetyl-CoA then enters the Krebs cycle (TCA cycle), driving the electron transport chain to generate massive amounts of ATP

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