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The proteoliposome aliquots of 100 l at a concentration of 8 mg/ml were flash-frozen with liquid nitrogen and stored at 80LC until use
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US EPA, 1998) inhalation toxicity studies from which no observed effect concentration (NOEC) or no observed adverse effect concentration (NOAEC) are derived to inform human health inhalation risk assessments (Ramanarayanan et al., 2022)
For context, semaglutide (injectable) and tirzepatide (injectable) show much larger average losses in high-quality trials, but they are injectable prescription medicines with different mechanisms and risk profiles
Toxic doses in research have been measured at 300-3,750 times higher than therapeutic ranges, providing substantial safety margins
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