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One of these Nrf2 targets, haem oxygenase-1 (HO-1), has two purposes in ferroptosis: promotion of ferroptosis via the generation of Fe 2+ from haem degradation, and deceleration of ferroptosis through the inhibition of oxidative stress

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The pathway activates PI3K/Akt/Nrf2 signaling in neural tissue

Diabetic ketoacidosis and the use of new hypoglycemic groups: Real-world evidence utilizing the Food and Drug Administration Adverse Event Reporting System