A phase I trial of PX-12, a small-molecule inhibitor of thioredoxin-1, administered as a 72-hour infusion every 21 days in patients with advanced cancers refractory to standard therapy
Right now, GLP-1s are just being prescribed off-label for PCOS (to people who meet the existing prescription criteria because of their weight and/or another related health condition)
References Antonio J, Candow DG, Forbes SC, Gualano B, Jagim AR, Kreider RB, Rawson ES, Smith-Ryan AE, VanDusseldorp TA, Willoughby DS, Ziegenfuss TN
Is FOXO4-DRI Approved for Human Use
Manufacturer liability : While drug manufacturers are not responsible for off-label uses, they can be held accountable if they failed to provide adequate warnings about known risks associated with the drug
Dermatologically, studies suggest that glutathione, when combined with tyrosinase inhibitors (like alpha arbutin), can significantly improve the appearance of hyperpigmentation