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Sulforaphane protects human umbilical vein cells against lipotoxicity by stimulating autophagy via an AMPK-mediated pathway

Depletion of GSH can lead to, among other things, mitochondrial dysfunction and cell death

The discrepancy between NADPH synthesis and consumption determines the intracellular NADPH level

Pako, P

There is evidence that polyphenols, curcumin, and lycopene curtail oxidative stress while improving the quality of treatment [231, 232]

For patients on established B12 injection therapy, monitoring is based primarily on clinical response and haematological parameters rather than routine serum B12 measurements, which may remain very high without indicating harm or overtreatment