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Osthole induces apoptosis and caspase-3/gsdme-dependent pyroptosis via nqo1-mediated ros generation in hela cells

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Concurrently, ROS impair endothelium-dependent vasodilation by inhibiting eNOS activity and accelerating NO degradation, while activating the NF-B pathway to release pro-inflammatory cytokines [315]

Role of PDS5B DNA binding in HR and DNA damage repair Given that the PDS5B 17A DNA binding mutation impairs the ability of PDS5B to enhance RAD51-mediated DNA strand exchange and is devoid of HR mediator activity (Figs

DYRK inhibitors, such as AZ Dyrk1B 33 and ID-8, increase the GLP-1 protein levels in GLUTag cells and the number of L and K cells in zebrafish and diabetic rats