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Key findings from this trial (PMID: 37350954) included: At 48 weeks, the 12 mg dose produced a mean weight reduction of 24.2% from baseline, compared to 2.1% in the placebo group

Research indicates that methylcobalamin has superior tissue retention compared to synthetic forms, meaning it stays in the body longer to support continuous nerve repair and homocysteine reduction

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Toxicology 271(1-2):512 Tu H, Xu C, Zhang W, Liu Q, Rondard P, Pin JP, Liu J (2010) GABAB receptor activation protects neurons from apoptosis via IGF-1 receptor transactivation