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It is neither confirmed nor refuted by data, and it sits on top of a mechanism literature that has itself been called into question

Macroscopic arthritis (swelling and redness) developed between days 6 and 23 after injection of autoantibodies to native and citrullinated cartilage proteins, which was enhanced by lipopolysaccharide (LPS) on day 5 (Fig

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doi:10.1016/j.metabol.2015.12.012 8

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