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The main differences between the two peptides are as follows: Mechanism of Action: Tirzepatide has an affinity to the receptors of another incretin hormone called Gastric Inhibitory Peptide (GIP) and also has some affinity to the GLP-1 receptors
Shelf logic is being redesigned around satiety, metabolic alignment and alcohol moderation
But the FDA has never approved phentermine for long-term continuous use, and the data supporting extended protocols is thin
It was the first weekly GLP-1 agonist