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Published in 2009, Tschp and DiMarchi's results provided the first demonstration that dual agonist drugs had potential to induce weight loss (Day, Ottaway, Patterson)

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The new triple agonist retitatrutide stimulates the glucose-dependent insulinotropic polypeptide (GIP), GLP-1 and glucagon receptors

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Choquette, S

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According to Novo Nordisk, the Wegovy pill is the first and only oral GLP-1 for weight loss in adults

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This doubles the weight loss effects seen in the initial liraglutide trials (2014) , suggesting that dosing regimens may be key to effective treatment (and differ from those used in T2D)

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Domestic freezers are not appropriate for IMP storage

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