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According to the in vivo and in vitro studies, the lipoxygenase inhibitor has exhibited a neuroprotective activity (Liu et al., 2015

Scientists have analyzed variations of gene expression under hypoxia conditions, but UPR-related genes can be excessively induced in the state of extreme hypoxia or moderate hypoxia

While that sounds cut-and-dried and makes a lot of sense, I want to note that not all studies agree and show decreases in brain volume and plasticity in depression

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Besides, those studies are referring to Aloe Vera alone