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In hypoxic tumor cores, activating HIF-1 prompts nuclear translocation and transcriptional upregulation of glycolytic machinery: glucose transporters (glucose transporter 1 (GLUT1)/GLUT3), HK2, PFK, and LDHAcollectively amplifying glycolytic flux (34)

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Staying hydrated between mealsrather than drinking large volumes during food intakealso supports gastric function

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