Outcomes with esophageal cancer radiation therapy
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Dietary intake is modest estimated at 100-150 mg/day from fruits, vegetables, and meats and much of this is broken down by digestive enzymes (gamma-glutamyltranspeptidase and dipeptidases) in the intestinal lumen before absorption [1][2]
However, NADPH can also be formed directly in the mitochondria by NAD(P) + transhydrogenase, mitochondrial/cytosolic NADP-dependent isocitrate dehydrogenase, or cytosolic malate dehydrogenase [125]
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10.3390/biomedicines12010127 [DOI] [PMC free article] [PubMed] [Google Scholar] Ducrest A, Amacker M, Mathieu YD, Cuthbert AP, Trott DA, Newbold RF, Nabholz M, Lingner J (2001) Regulation of human telomerase activity: repression by normal chromosome 3 abolishes nuclear telomerase reverse transcriptase transcripts but does not affect c-Myc activity