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The pharmacokinetics of semaglutide were evaluated following a single dose of 0.5 mg semaglutide in a study of patients with different degrees of hepatic impairment (mild, moderate, severe) compared with subjects with normal hepatic function

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A small effect of injection site shows up in absorption research, with bioavailability roughly 12 percent lower in the thigh compared with the abdomen

The risks of injecting unlicensed, often poorly manufactured compounds are real and not adequately offset by the potential benefits, particularly when well-evidenced alternatives are available

Aaboe K, Krarup T, Madsbad S, Holst JJ

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