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[32] MSTN BLOCKADE AS A STRATEGY TO COUNTERACT GLP-1-INDUCED MUSCLE LOSS GLP-1 is a hormone secreted from intestinal L cells following food intake

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Metformin and thiazolidinedione have additional advantage of improving insulin resistance and decreasing visceral fat accumulation

Why this trial matters: First large Phase III evidence of biopsy-confirmed histologic benefit with a metabolic drug in MASH Demonstrates semaglutides impact beyond weight loss to disease-modifying liver effects Supports expanding GLP-1 therapeutics into liver disease care amid a high unmet need Ianalumab Meets Endpoints in Phase III Sjgrens Disease Trials (NEPTUNUS-1 & 2) Novartis reported that both Phase III studies of ianalumab achieved their primary endpoints in patients with Sjgrens disease, offering the first targeted therapy with statistically significant disease activity reduction in this chronic autoimmune disorder

As more people explore peptide therapy, one common question arises: should you take BPC 157 orally in capsule form or by injection