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There are great variations in nuclear GSH concentration and its regulation mechanisms during the cell cycle since cells starting the proliferation phase have high levels of nuclear GSH, while resting cells have similar or lower GSH levels in the nucleus than in the cytoplasm (68, 72, 73)
"Environmental-friendly catalysts learned from Vitamin B 12 -dependent enzymes" (PDF)
[DOI] [PMC free article] [PubMed] [Google Scholar] 114.Pierce GB, Parchment RE, Lewellyn AL
Pharmaceutics 17 (1), 90
A HD derivative was found to suppress HSC activation and proliferation by targeting PTEN/AKT pathway, which means it is a potential therapeutic choice in treating liver fibrosis (Li et al., 2017)
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