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The peptide spreads into the circulation and does five things nearly simultaneously: it drives insulin secretion from pancreatic beta cells, suppresses glucagon from alpha cells, slows gastric emptying, and sends satiety signals to the hypothalamus and brainstem, telling the brain the meal is enough

EGR-1 is a gene that is considered to respond immediately and is potentially involved in the generation of cytokines and growth factors, as well as the early formation of extracellular matrix components like collagen

This article was reviewed by Craig Primack, MD, FACP, FAAP, FOMA

Drafting the work or revising: A.B.M.K.H., M.S.A., D.D., T.S., F.T.Z.A., L.N