soul trial oral semaglutide cardiovascular outcomes trial results (NEJM 2025): led to a 14% ↓ in major CV events vs placebo in T2DM with ASCVD or CKD — no ↑ in serious AEs. #Semaglutide #CardioDiabetes #updatesinmedicine Oral Semaglutide Reduces Cardiovascular Events

Still, the findings open compelling new avenues of investigation into how GLP-1 drugs anti-inflammatory effects may help with other conditions such as heart failure, sleep apnea and chronic kidney disease, Said says

One reaction detects genotypes 1a, 1b, and 3a

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Non-athletes use it for better memory and mental clarity

Increased Hunger A change in appetite or mild GI discomfort may be noticed

Clearance occurs primarily via enzymatic degradation by serum and tissue peptidases