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Specifically, SP and SP@M increased the LC3-mediated autophagy as well as strengthened the ubiquitin-mediated proteasomal degradation toward KEAP1 (Figs

Compared with phagocytic cells, the epithelial cells produce ROS at a much lower, which are involved in redox-sensitive signaling pathways but may not directly eradicate H

In addition, KPV expands research applications

Iron deficiency or iron overload can severely disrupt physiological functions

For this reason, Kappa GSTs and mPGES-1 (microsomal ProstaGlandin E-Synthase type 1), one subclass of MAPEGs (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) (Bresell et al., 2005), enzymes often integrated into the GST superfamily, are not considered here, even though some terrestrial plants and algae possess at least one mPGES-1 representative

These toxic aggregates increase oxidative stress in the cell, forming reactive oxygen species and damaging cell structures