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Colour: Sunset yellow fcf EMPACON MET 5/1000 TABLET - Empagliflozin 5 Mg, Metformin Hydrochloride 1000 Mg, Excipients Q.s

Pillon, Gunnar Schulte, Roger J

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If your genetics suggest reduced GIPR function but strong MC4R regulation, a combination approach like GLP-Squared (semaglutide plus tirzepatide) could unlock better outcomes

The positive control used was topiroxostat, which showed an IC 50 of 17 nM, very close to compound 72 , the most active compound in the study (Figure 23)