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Problems in GLP-1RA development Cost-effective and reliable trial endpoints for MASLD medication Assessing long-term liver benefits in clinical trials has remained a complex issue

Increases risk of future Type 2 diabetes- 30-33 % develop type 2 diabetes within years

Instead of a quick note that disappears, GLP-1 medications (like semaglutide) are engineered to be long-lasting

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(2013) 346:f2059

Esta combinacin es objeto de estudio habitual en la investigacin bioqumica por su interaccin con los mecanismos de sealizacin peptdica y los procesos de regulacin molecular