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[1] [4] The only FDA-approved forms of tirzepatide are the pre-filled, single-dose injection pens marketed as Mounjaro (for type 2 diabetes) and Zepbound (for chronic weight management)

doi: 10.3389/fphar.2026.1860254 Received 20 April 2026 Revised 06 July 2026 Accepted 13 July 2026 Published 27 July 2026 Volume 17 - 2026 Edited by Slvio Terra Stefanello, University of Mnster, Germany Reviewed by Wenxu Pan, Guangzhou Medical University, China Asad Khan, Sichuan Agricultural University, China Updates Copyright 2026 Wang, Liang, Guo, Sun, Sun, Chen and Xu

Coupling of the T1Rs to gustducin is thought to stimulate phosphodiesterase activity, leading to the hydrolysis of cAMP (149)

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