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The BIOM file output from the DADA2 pipeline and the DECIPHER-aligned FastTree phylogenetic tree were input into QIIME (v1.9.1) and the scripts in the Supplementary Materials (QIIME Scripts compilation) were used to establish the alpha diversity metrics of Chao1 richness estimate, Simpsons evenness measure E, Shannon diversity index H, Simpsons diversity index, and Faiths phylogenetic diversity metric (whole tree) as well as the beta diversity measures of unweighted and weighted UniFrac analyses (the latter of which factors in ASV abundance 37 ) and BrayCurtis dissimilarity analysis

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At higher doses, it is also absorbed by passive diffusion across the gut wall, independently of intrinsic factor

Note: Patients with a sulfa allergy should not take this injection

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Overusing injections or receiving them too frequently without medical supervision may not provide additional benefits and could increase the risk of side effects