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The evidence behind the treatment: Consider the clinical research supporting its effectiveness and safety

doi: 10.1073/pnas.1322269111 22 ChenC.YouL

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Nat Metab 2(5):413431 Nestor JJ, Parkes D, Feigh M, Suschak JJ, Harris MS (2022) Effects of ALT-801, a GLP-1 and glucagon receptor dual agonist, in a translational mouse model of non-alcoholic steatohepatitis

Together, increased intraplaque cellular death and dysfunctional efferocytosis as a result of G6PD-d may accelerate plaque growth, necrotic core formation and the development of an inflammatory plaque microenvironment 106,107 (Fig